Preterm premature rupture of membranes (PPROM) complicates up to 40% of deliveries less than 37 completed weeks gestation. Absence of clinical symptoms means that fetal infection can be missed and later complications are significantly higher. There is thus a real need for non-invasive antenatal assessment of the early signs of placental inflammation. This study combines an efficient multimodal Diffusion-Relaxation acquisition with dedicated analysis to study the placental phenotype associated with PPROM. Initial results indicate that multi-modal MRI measurement of placental function is linked to eventual gestational age at delivery.
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