Abstract #0815
Structural-functional interplay of the human placenta: in-vivo study using Pseudocontinuous Arterial Spin Labeling
Daphna Link1, Netanell Avisdris1,2, Xingfeng Shao3, Liat Ben Sira4,5, Liran Hiersch6, Ilan Gull7, Danny J.J. Wang8, and Dafna Ben Bashat1,4
1Sagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel, 3Laboratory of FMRI Technology (LOFT), USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, 4Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel, 5Division of Pediatric Radiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 6Division of Obstetrics and Gynecology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 7Ultrasound Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 83Laboratory of FMRI Technology (LOFT), USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States
Synopsis
Adequate placental structure and function are crucial for fetal and maternal health. Here we assessed late-gestation placental perfusion (N=50, GA=31-38 weeks) using pseudocontinuous arterial-spin-labeling and radiomics feature-extraction, and their association with umbilical-cord insertion-site and the risk of fetal-growth-restriction (FGR). Increased blood-flow and arterial-transit-time were detected in our normal cases compared to earlier gestation as reported previously. Perfusion features differences were detected in placentas with marginal compared to central cord-insertion, indicating higher intensity heterogeneity. No differences were found between normal and FGR placentas. This study provides normal late-gestation placental perfusion values based on a large cohort, and implies on structural-functional associations.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
