The use of PET/MRI scanners is an innovative approach to stage prostate cancer (PCa) and the combined use of both 68Ga-PSMA and 68Ga-DOTA-RM2 radiotracers can improve disease staging by providing different metabolic aspects of the tumour. In the present study, 13 patients with high-risk PCa undergoing 68Ga-PSMA and 68Ga-DOTA-RM2 PET/MRI before radical prostatectomy have been included, with availability of histology as gold standard to validate intraprostatic findings and local extension. Our results suggest that the use of PET/MRI with a dual tracer approach can improve PCa staging, by providing complementary information ameliorating disease characterization.
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