IVIM MRI provides measurements of diffusion and perfusion, which has been shown to be predictive of prognosis, responsive to chemoradiotherapy, and correlated with DCE MRI in cervical cancer. We hypothesized that IVIM in cervical cancer patients would be sensitive to CCRT, and hence our objective was to first investigate changes in IVIM in cervical cancer patients undergoing adjuvant CCRT and evaluate the relationship between these metrics with changes in tumor volume and PET. Preliminary results show that IVIM measurements are related to both PET and changes in overall tumor volume and may reflect changes in the tumor microenvironment during treatment.
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