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Abstract #0894

Diffusion Tensor Imaging Helps to Differentiate Neuromyelitis Optica Spectrum Disorders and Multiple Sclerosis-Related Optic Neuritis

Yan Xie1, Yan Zhang1, Weiyin Vivian Liu2, and Wenzhen Zhu1
1Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2GE Healthcare, MR Research China, Beijing, China


The purpose of this study was to assess the differences in the patterns of NMOSD and MS-related optic nerve damage by DTI. In this study, the intraorbital optic nerve was divided anatomically in three equal parts. We found that NMOSD-related optic neuritis exhibited extensive optic nerve damage, particularly in the posterior segment of the optic nerve, whereas MS-related optic neuritis tended to be more anterior-middle optic nerve damage. In addition, the combination of FA with conventional MRI showed better differential diagnostic efficacy for NMOSD and MS-related optic neuritis.

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