In perfusion imaging with arterial spin labeling (ASL), the labeling plane is located further away from the isocenter of the scanner, than the imaging volume. This can result in offsets in resonance frequencies which can lead to imperfect inversion and hence lower labeling efficiency. In this study, a perfusion phantom is used to study the influence of off-resonance on two arterial spin labeling schemes, in order to determine whether an additional F0 determination at the labelling plane is the redeeming factor for successful ASL MRI independent of the labeling scheme used.
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