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Abstract #0906

F0 determination at the labeling plane: the neglected factor for successful pCASL perfusion MRI

Lena Vaclavu1, Kim van de Ven2, and Matthias van Osch1
1C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 2Philips Healthcare, Best, Netherlands

Synopsis

In perfusion imaging with arterial spin labeling (ASL), the labeling plane is located further away from the isocenter of the scanner, than the imaging volume. This can result in offsets in resonance frequencies which can lead to imperfect inversion and hence lower labeling efficiency. In this study, a perfusion phantom is used to study the influence of off-resonance on two arterial spin labeling schemes, in order to determine whether an additional F0 determination at the labelling plane is the redeeming factor for successful ASL MRI independent of the labeling scheme used.

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