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Abstract #0911

A vortical phantom for ASL perfusion MRI

Aaron Oliver-Taylor1 and Xavier Golay1,2
1Gold Standard Phantoms, London, United Kingdom, 2Queen Square Institute of Neurology, University College London, London, United Kingdom


Most perfusion phantoms that have been created make use of porous media to simulate the microvasculature, however their characterisation introduces additional uncertainties into a perfusion measurement. We take inspiration from a recently published impinging jet perfusion phantom and presenting a phantom that makes use of vortices to mix and disperse the perfusion signal. Multi post labelling delay pCASL data was acquired, and fit to the general kinetic model. By assuming the measured perfusion equates to the equivalent perfusion from the systemic flow rate the labelling efficiency can be estimated, and the resultant measured and fitted signal curves closely match.

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