PICORE-ASL using tr-FOCI pulses during labelling typically generates high power deposition at 7T. The current study introduces an asymmetric tr-FOCI pulse for PICORE-ASL to achieve SAR reduction. Results from simulations, phantom and in vivo experiments demonstrate the SAR reduction that can be achieved by using the asymmetric pulses without sacrificing inversion efficiency, slice profiles or CBF measurement.
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