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Abstract #0920

The value of semi-quantitative parameters of Dynamic Contrast-Enhanced MRI(DCE-MRI) to predict the expression of P53 in the ovarian cancer

Xulun Lu1, Ye Li1, Qingling Song1, and Ailian Liu1
1First Affiliated Hospital of Dalian Medical University, Dalian, China


P53 is a tumor suppressor gene,TP53-mutated tumors in general have an aggressive phenotype and are characterized by poor differentiation, increased invasiveness, and high metastatic potential[1]。The early enhancement rate reflects the blood perfusion in the early enhancement stage of the lesion. Tumor exhibits a higher early enhancement rate with more abundant the blood supply of the tumor. Our study proved that the wash-in rate of ovarian cancer in the p53 positive group was higher than that in the P53 negative group.

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