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Abstract #0921

A Pilot Evaluation of DKI in Characteristics and Diagnosis of Ovarian Cancer of p53 Status

Shiqi Chen1, Yulin Chen1, Ye Li1, and Ailian Liu1
1the First Affiliated Hospital of Dalian Medical University, Dalian, China


The identification and treatment of ovarian cancer(OC) has always been a problem that plagues us[1]. Mutations in the p53 gene showed significantly up-regulation in human OC tissues and was closely associated with the development of human OC. This work aimed at exploring the value of Diffusion kurtosis imaging (DKI) for characteristics and diagnosis of ovarian cancer of p53 status. The results showed that FA provided a promising performance (AUC =0.742 , sensitivity = 100%, specificity = 43.7%) in evaluating p53 status and OC.

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