Despite its prevalence, methods for investigating lymphoedema (chronic tissue swelling due to abnormal lymphatic functioning) remain limited. Dynamic Contrast-Enhanced Magnetic Resonance Lymphangiography (DCE-MRL) allows identification of lymph vessels in both healthy and lymphoedematous limbs, however quantitative analyses are lacking. DCE-MRL data was acquired for 30 minutes in lymphoedematous (n=7) and healthy limbs (n=4), with estimates of lymphatic vessel signal characteristics compared between groups. Maximum enhancement compared to baseline was significantly increased in healthy volunteers, while other metrics were similar. Larger groups and longer imaging sessions are likely required to detect additional differences.
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