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Abstract #0971

The relationship between structural asymmetry and shear stiffness asymmetry in the human brain

Lily Xiang1, Lucy Victoria Hiscox2, Curtis L. Johnson3, and Neil Roberts1
1University of Edinburgh, Edinburgh, United Kingdom, 2University of Bath, Bath, United Kingdom, 3University of Delaware, Newark, DE, United States

Synopsis

On average the human brain has a global structural asymmetry comprising a counter-clockwise twist in the transverse plane and which is referred to as the cerebral torque. We have investigated whether there is a relationship between the magnitude of the torque and measures of brain shear stiffness obtained using Magnetic Resonance Elastography (MRE) in a group of Older Adults (AD) and a group of patients with Alzheimers DIsease (AD).

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