Self-gated 3D Stack-of-Spirals Ultra-Short Echo-Time Pulmonary imaging at 0.55T
Ahsan Javed1, Rajiv Ramasawmy1, Kendall O’Brien1, Christine Mancini1, Pan Su2, Waqas Majeed2, Thomas Benkert3, Himanshu Bhat2, Anthony F. Suffredini4, Ashkan Malayeri5, and Adrienne E Campbell-Washburn1
1Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, 2Siemens Medical Solutions USA Inc., Malvern, PA, United States, 3Siemens Healthcare GmbH, Erlangen, Germany, 4Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, United States, 5Department of Radiology and Imaging Sciences, Clinical Center, Department of Health and Human Services, National Institutes of Health, Bethesda, MD, United States
High-performance 0.55T MRI is promising for lung imaging due to the reduced susceptibility artifacts. However, high-resolution lung imaging is still challenged by low proton density and SNR. 3D spiral acquisitions can be used to improve SNR-efficiency, but these readouts are susceptible to trajectory errors and blurring from concomitant-fields, which are amplified at lower field strengths. Here we present a self-gated, ultra-short echo-time, stack-of-spirals acquisition which leverages rapid inline corrections for trajectory imperfections, trajectory dependent navigator signal fluctuations, and concomitant-fields to enable robust 1.75mm isotropic lung imaging at 0.55T. We also demonstrate our technique in healthy-volunteers, patients with lung-nodules and COVID-19.
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