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Abstract #1001

Analysis of resting state functional connectivity of white matter tracts in spinal cord of squirrel monkey using Graph Theory

Anirban Sengupta1, Arabinda Mishra1, Feng Wang1, Li Min Chen1, and John C Gore1
1Vanderbilt University Medical Center, Nashville, TN, United States


The goal of this study was to investigate the nature of spontaneous BOLD fluctuations in white-matter (WM) of spinal-cord and to use these to identify the intrinsic functional architecture of WM tracts and their correlations with the gray-matter (GM) hubs. Connectivity measures were obtained using resting state BOLD signals between WM-WM and WM-GM regions, followed by network analysis using graph-theory. We found WM and GM hubs on the dorsal side exhibit greater temporal correlation as exhibited by their stronger node strength in resting state. Also, within segment WM-WM and WM-GM correlations were found to be stronger than those between segments.

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