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Abstract #1035

Prospective correction of multi-shot diffusion imaging using motion compensation and dual-speed EPI

Kevin Moulin1,2, Tyler E Cork3,4, Thomas Troalen5, Daniel Ennis3,4, Pierre Croisille1,2, and Magalie Viallon1,2
1CREATIS, Lyon, France, 2Department of Radiology, University Hospital Saint-Etienne, Saint Etienne, France, 3Department of Radiology, Stanford University, Stanford, CA, United States, 4Division of Radiology, Veterans Administration Health Care System, Palo Alto, CA, United States, 5Siemens Healthcare SAS, Saint-Denis, France


Multi-shot (MS) reduces image distortion in EPI caused by B0 field inhomogeneity and enables higher resolution diffusion imaging. However, interaction between physiologic motion and diffusion encoding gradients leads to strong image aliasing artifacts in MS-EPI due to phase discrepancies. We propose prospective strategies to reduce shot-to-shot phase variation for interleaved phase-segmented diffusion MS-EPI. First and second order motion compensated diffusion gradient waveforms and dual-speed EPI with oversampled k-space center were evaluated as a shot-to-shot phase mitigation strategy. Validations were performed in silico, in vitro, and in vivo in the brain, liver, and heart.

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