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Abstract #1036

Highly Asymmetric Acquisitions for Diffusion MRI Tractography

Manoj Shrestha1, Pavel Hok1,2, Ulrike Nöth1, and Ralf Deichmann1
1Brain Imaging Center (BIC), Goethe University Frankfurt, Frankfurt am Main, Germany, 2Department of Neurology, Palacky University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic


Frequently, diffusion-weighting modules such as schemes based on the Stejskal-Tanner concept or the STEAM are combined with EPI readout for fast k-space sampling. In contrast to standard sequences, highly asymmetric spin-echo and highly asymmetric STEAM sequences (HASE, HASTEAM) offer shorter TE, maintaining constant diffusion preparation duration, independent of the matrix-size. In this study, HASE and HASTEAM sequences were implemented for neuronal fibre tracking, and results were compared with standard sequences. Both asymmetric sequences HASE and HASTEAM allow for more accurate estimations of the subsidiary fibre orientations, which may considerably improve the quality and quantity of the detected fibre tracts.

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