Abstract #1047

Optimization of a breast EPI-DWI protocol with high b-values and anterior-posterior phase-encoding direction: initial results

Ana E Rodríguez-Soto¹, Summer J Batasin¹, Lauren K Fang¹, Michael Carl², Haydee Ojeda-Fournier¹, Kathryn E Keenan³, and Rebecca A Rakow-Penner^1,4

¹Radiology, University of California, San Diego, La Jolla, CA, United States, ²GE Healthcare, University of California, San Diego, La Jolla, CA, United States, ³National Institute of Standards and Technology, Boulder, CO, United States, ⁴Bioengineering, University of California, San Diego, La Jolla, CA, United States

Synopsis

Diffusion-weighted imaging (DWI) acquired with echo-planar imaging (EPI) is utilized in breast MRI protocols to evaluate cancer lesions. While clinical implementation is limited by the distortion artifacts which affect EPI, methods such as reverse polarity gradient (RPG) and data collection with reduced field-of-view (FOV) have been used to reduce distortion. Evaluating these methods in minimizing distortion for images acquired with parallel imaging (PI) is a promising approach to improve EPI-DWI breast imaging. Here, we evaluated the distortion magnitude of EPI-DWI data collected with and without PI on a breast phantom and tested the feasibility of this protocol in vivo.

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