The integration of deep learning priors into regularized CG-SENSE reconstructions enables high quality MR images to be generated from noisy, undersampled data. The regularization parameter in these methods can be tuned to control the level of denoising, allowing a network to generalize to novel SNR conditions without retraining. However, manual tuning of the regularization parameter can be time consuming. This work presents a data-driven method for automatic regularization selection using commonly acquired noise calibration data. Results indicate the method generalizes across clinically relevant imaging scenarios and provides diagnostically equivalent image quality to that obtained by manual parameter tuning.
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