We determined day-to-day variation and intra-session reproducibility of 31P-MRS-based hepatic phosphorus metabolite quantification. To this end, we compared a standard single loop with a custom-created quadrature surface coil. Absolute concentrations of γ-adenosine triphosphate and inorganic phosphate were assessed in 7 volunteers with both coils. Both coils showed comparable day-to-day and intra-session CVs < 10 %. Metabolite concentrations determined by the two coils were similar. Therefore, both coils yield robust absolute concentrations of hepatic phosphorous metabolites. The quadrature coil allows measurements at a higher distance from the coil which can be important for the application in obese patients.
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