Endogenous assessment of myocardial injuries using T1-rho mapping: comparison to T1 mapping, T2 mapping and late gadolinium enhancement imaging
Aurelien Bustin1,2,3, Xavier Pineau2, Soumaya Sridi2, Pierre Jaïs1,4, Matthias Stuber1,3,5, and Hubert Cochet1,2
1IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux – INSERM U1045, Bordeaux, France, 2Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France, 3Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 4Department of Cardiac Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France, 5CIBM Center for Biomedical Imaging, Lausanne, Switzerland
Myocardial T1-rho (T1ρ) mapping is a promising technique which reveals new insights about the macromolecular content of biological tissues. The idea that T1ρ mapping can be used to quantify myocardial fibrosis without contrast agent opens the door to new clinical capabilities. Yet, the tissue determinants driving T1ρ changes are still unclear, and the applicability of the technique to the broad spectrum of myocardial injuries remains uncharted territory. In the present study, we aim to identify clinical correlates of myocardial T1ρ and to examine how myocardial T1ρ values change under various clinical scenarios.
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