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Abstract #1109

3D whole-heart free-breathing T1⍴ quantification: a preliminary clinical evaluation.

Carlos Velasco1, Anastasia Fotaki1, Haikun Qi1, Rene M. Botnar1, and Claudia Prieto1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Synopsis

T1⍴-CMR allows the detection of scarred myocardial tissue without the need of an exogenous contrast. However, the generation of a single-slice T map requires sequential acquisitions under several breath-holds to acquire the T1⍴-weighted images at different spin-lock times, leading to long, inefficient scan times. We recently proposed a free-breathing motion-compensated 3D whole heart T mapping technique with near-isotropic spatial resolution (1.7×1.7×2 mm3) and predictable and clinically feasible scan In this work time (~8min). Here, we extend this technique to incorporate non-rigid motion corrected reconstruction and validate the proposed technique on subjects with suspected myocardial infarction.

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