3D super-resolution motion-corrected cardiac T1 mapping
Simone Hufnagel1, Selma Metzner1, Christoph Stefan Aigner1, Jeanette Schulz-Menger2,3,4, Tobias Schaeffter1,5,6, and Christoph Kolbitsch1
1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 2Charité Medical Faculty University Medicine, Berlin, Germany, 3Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center (ECRC), DZHK partner site Berlin, Berlin, Germany, 4Department of Cardiology and Nephrology, HELIOS Klinikum Berlin Buch, Berlin, Germany, 5School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 6Department of Biomedical Engineering, Technical University of Berlin, Berlin, Germany
Cardiac T1 mapping provides valuable quantitative information about fibrosis in various cardiac diseases. Due to SNR limitations and the motion of the heart during imaging, often 2D T1 Maps with only low through-plane resolution (i.e. slice thickness of 6-8 mm) can be obtained. We present a model-based super-resolution reconstruction which combines multiple stacks of 2D acquisitions with 6 mm slice thickness and generates 3D high-resolution T1 maps. Cardiac and residual respiratory motion is corrected for. The approach was evaluated in native T1 mapping in three healthy volunteers and provided precise T1 maps with improved visualization of small structures.
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