The importance of optimized post-processing for accurate T1-mapping using shMOLLI: A phantom and in vivo evaluation at 3 T
Linnéa Andersson1, Pär-Arne Svensson2, Charlotte De Lange2, and Kerstin Lagerstrand1,3
1Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, 2Department of Paediatric Radiology, Queen Silvia Children's hospital, Sahlgrenska University Hospital, Gothenburg, Sweden, 3Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
We demonstrate the effect of not having relevant post-processing algorithm implemented when using the shMOLLI scan sequence for T1-mapping of myocardium and propose an optimization strategy where we use only the five first acquired images in post-processing. Phantom and in vivo measurements of T1-values in myocardium and blood pool in a pediatric population show the importance of using relevant post-processing: a large heart rate dependence is introduced in estimated T1-values without it. This heart rate dependency can, however, be effectively reduced by using only the five first acquired images in post-processing, resulting in measurements with high accuracy.
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