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Abstract #1188

Hyperpolarized 13C imaging at moderate field strengths: SNR considerations and in-vivo feasibility at 1.5T

Maximilian Fuetterer1, Julia Traechtler1, Andreas Dounas1, Tobias Hoh1, Mohammed Albannay1, and Sebastian Kozerke1
1Institute for Biomedical Engineering, University and ETH Zurich, Z├╝rich ETH-Zentrum, Switzerland

Synopsis

Motivated by the fact that the hyperpolarized MRI signal does not quadratically scale with field strength as for conventional MRI at thermal equilibrium, the achievable SNR at reduced field strengths is explored. It is demonstrated that for larger coil diameters, sample noise dominates electrical noise at 1.5T and achievable SNR becomes comparable to 3T. By adaptively reducing acquisition bandwidth to the reduced spectral span and given longer T2* decay, effective SNR at 1.5T exceeds 3T. Feasibility is demonstrated with the first in-vivo data acquired on a clinical 1.5T system using hyperpolarized 13C pyruvate.

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