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Abstract #1218

Improved visualization of intracranial peripheral arteries with multiple 2D slice ASL-MRA and super-resolution

Yuriko Suzuki1, Peter Jezzard1, Ioannis Koktzoglou2,3, and Thomas Okell1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Department of Radiology, NorthShore University HealthSystem, Evanston, IL, United States, 3Pritzker School of Medicine, University of Chicago, Chicago, IL, United States

Synopsis

In recent years, magnetic resonance angiography (MRA) using arterial spin labeling (ASL) technique has been developed aiming to be a non-invasive potential alternative to X-ray angiography. When blood flow is slow (e.g. in elderly patients, especially with steno-occlusive diseases), however, ASL-MRA suffers from poor vessel visualization, which hinders its clinical utility in those patients. In this study, instead of using a 3D volume acquisition commonly used in brain MRI, we propose to separately scan multiple 2D slices to reduce the saturation of arterial blood signal and improve the visualization of small peripheral arteries, in combination with a super-resolution reconstruction.

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