Abstract #1233

Dynamic resting state connectivity of the default mode, salience and central executive networks in adolescents with concussion

Rachelle A. Ho¹, Saurabh B Shaw², Nicholas A Bock¹, Carol DeMatteo³, Michael D Noseworthy⁴, and Geoffrey Hall¹

¹Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada, ²Department of Psychiatry, Western University, London, ON, Canada, ³School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada, ⁴Department of Electrical & Computer Engineering, McMaster University, Hamilton, ON, Canada

Synopsis

Our study evaluated the dynamic functional connectivity of adolescents with concussion in comparison to healthy controls using (1) sliding window ROI-to-ROI and (2) sliding window graph theory analyses. Adolescents with concussion exhibited higher between-network connectivity between the salience network and central executive network, but reduced between-network connectivity between the default mode network to both the salience and executive networks. This suggests lower default mode network integration and engagement during rest following concussion in adolescents.

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