Dynamic resting state connectivity of the default mode, salience and central executive networks in adolescents with concussion
Rachelle A. Ho1, Saurabh B Shaw2, Nicholas A Bock1, Carol DeMatteo3, Michael D Noseworthy4, and Geoffrey Hall1
1Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada, 2Department of Psychiatry, Western University, London, ON, Canada, 3School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada, 4Department of Electrical & Computer Engineering, McMaster University, Hamilton, ON, Canada
Our study evaluated the dynamic functional connectivity of adolescents with concussion in comparison to healthy controls using (1) sliding window ROI-to-ROI and (2) sliding window graph theory analyses. Adolescents with concussion exhibited higher between-network connectivity between the salience network and central executive network, but reduced between-network connectivity between the default mode network to both the salience and executive networks. This suggests lower default mode network integration and engagement during rest following concussion in adolescents.
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