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Abstract #1261

The Compressed Sensing MP2RAGE as a surrogate to the MPRAGE for neuro-imaging at 3T

Aurélien J Trotier1, Bixente Dilharreguy2, Serge Anandra3, Nadège Corbin1, William Lefrançois1, Valery Ozenne1, Sylvain Miraux1, and Emeline Julie Ribot1
1Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS, Bordeaux, France, 2UMS3767, CNRS, Bordeaux, France, 3UMS3767, Université de Bordeaux, Bordeaux, France

Synopsis

A Compressed Sensing Magnetization prepared Two Rapid Gradient Echo (CS-MP2RAGE) sequence was developed to provide images in <10min including reconstruction time. It was applied on 13 participants each scanned 3 to 4 times with repositioning. Compared to the standard MPRAGE sequence, it provides higher contrast morphological images. Similar intra-volunteer variabilities in volume segmentations of the brain structures were obtained. Additionally, high resolution T1 maps provided T1 values of white and gray matters and several deep grey nuclei consistent with the literature, and show very low variability (<1%). The CS-MP2RAGE can be used in future clinical research protocols.

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