Abstract #1286

Fast 23Na-T2* relaxation parameter estimation in the human brain

Frank Riemer¹, Marco Reisert², Bhavana S Solanky³, Claudia AM Wheeler-Kingshott^3,4,5, Golay Xavier³, Renate Grüner^1,6, and Ivan I Maximov⁷

¹MMIV, Haukeland University Hospital, Bergen, Norway, ²University Medical Center, Freiburg, Germany, ³UCL Queen Square Institute of Neurology, London, United Kingdom, ⁴Brain Connectivity Centre, IRCCS Mondino Foundation, Pavia, Italy, ⁵Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy, ⁶Department of Physics and Technology, University of Bergen, Bergen, Norway, ⁷Western Norway University of Applied Sciences, Bergen, Norway

Synopsis

Due to quadrupolar interactions, 23Na exhibits a bi-exponential T2. Previous approaches to estimate T2* have relied on simple least squares approaches or treating it as an inverse problem. Here we present a fast method based on Bayesian estimation and illustrate it on an in vivo dataset.

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