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Abstract #1286

Fast 23Na-T2* relaxation parameter estimation in the human brain

Frank Riemer1, Marco Reisert2, Bhavana S Solanky3, Claudia AM Wheeler-Kingshott3,4,5, Golay Xavier3, Renate Grüner1,6, and Ivan I Maximov7
1MMIV, Haukeland University Hospital, Bergen, Norway, 2University Medical Center, Freiburg, Germany, 3UCL Queen Square Institute of Neurology, London, United Kingdom, 4Brain Connectivity Centre, IRCCS Mondino Foundation, Pavia, Italy, 5Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy, 6Department of Physics and Technology, University of Bergen, Bergen, Norway, 7Western Norway University of Applied Sciences, Bergen, Norway


Due to quadrupolar interactions, 23Na exhibits a bi-exponential T2. Previous approaches to estimate T2* have relied on simple least squares approaches or treating it as an inverse problem. Here we present a fast method based on Bayesian estimation and illustrate it on an in vivo dataset.

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