Non-rigid Motion-compensated Whole-heart 18F-FDG PET and 3D T2 mapping in a hybrid PET-MR system
Alina Schneider1, Camila Munoz1, Alina Hua1, Sam Ellis1, Sami Jeljeli2, Karl P Kunze1,3, Radhouene Neji1,3, Eliana Reyes1, Tevfik F Ismail1, René M Botnar1, and Claudia Prieto1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2PET Centre, St Thomas’ Hospital, King’s College London & Guys and St Thomas’ NHS Foundation Trust, London, United Kingdom, 3MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom
Simultaneously acquired 18F-FDG PET-MR imaging and quantitative 2D T2-mapping have been suggested for improved diagnostic accuracy of cardiac sarcoidosis, however misregistration between imaging modalities makes clinical interpretation challenging. Here we used a recently proposed free-breathing motion-corrected 3D whole-heart T2-mapping sequence acquired simultaneously with 18F-FDG PET at a 3T PET-MR system. This approach enables the non-rigid motion-correction for both the 3D T2-mapping and the PET data to the same respiratory position, resulting in aligned volumes for improved clinical interpretation. In this study, we tested this approach in a patient with suspected cardiac sarcoidosis.
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