Assessment of gadolinium contrast in the brain using a compressed sense 3D Look Locker sequence after intrathecal contrast administration
Tryggve Holck Storås1, Svein Are Vatnehol2,3, Geir Ringstad4, Kyrre Holck Emblem5, and Per Kristian Eide6,7
1Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway, 2The Intervention Centre, Oslo University Hospital, Oslo, Norway, 3Faculty of Health and Social Sciences, University of South-Eastern Norway, Drammen, Norway, 4Department of Radiology, Oslo University Hospital, Oslo, Norway, 5Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway, 6Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway, 7Department of Neurosurgery, Oslo University Hospital – Rikshospitale, Oslo, Norway
Quantitative assessment of T1 enhancement after intrathecal administration of Gd-contrast may remove present challenges due to image scaling varying between acquisitions. The compressed SENSE technique allow 3D-Look-Locker-TFE acquisitions with isotropic 1 mm resolution and full brain coverage to be run in clinically feasible times. A clinical example is demonstrated and a small phantom study exploring further improvements based on trade-offs between undersampling and reduced saturation effects is presented.
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