Abstract #1296

Assessment of gadolinium contrast in the brain using a compressed sense 3D Look Locker sequence after intrathecal contrast administration

Tryggve Holck Storås¹, Svein Are Vatnehol^2,3, Geir Ringstad⁴, Kyrre Holck Emblem⁵, and Per Kristian Eide^6,7

¹Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway, ²The Intervention Centre, Oslo University Hospital, Oslo, Norway, ³Faculty of Health and Social Sciences, University of South-Eastern Norway, Drammen, Norway, ⁴Department of Radiology, Oslo University Hospital, Oslo, Norway, ⁵Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway, ⁶Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway, ⁷Department of Neurosurgery, Oslo University Hospital – Rikshospitale, Oslo, Norway

Synopsis

Quantitative assessment of T1 enhancement after intrathecal administration of Gd-contrast may remove present challenges due to image scaling varying between acquisitions. The compressed SENSE technique allow 3D-Look-Locker-TFE acquisitions with isotropic 1 mm resolution and full brain coverage to be run in clinically feasible times. A clinical example is demonstrated and a small phantom study exploring further improvements based on trade-offs between undersampling and reduced saturation effects is presented.

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