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Abstract #1300

Identifying the role of free water in human cortical macroscopic organization

Lei Wei1, MIng Ding1, yuwen zhang1, and he wang1,2
1Institute of Science and Technology for Brain-Inspired Intel, ShangHai City, China, 2Human Phenome Institute, Fudan University, Shanghai, China, ShangHai City, China

Synopsis

Free water imaging is a novel tool to study human brain. Recently, the free water has been used in aging disease researach. However, the role of free water in human cortex macroscopic is still unknown. This work shows the relationship between the cortical free water and the cortical thickness, and investigate the underlying molecular and genetic mechanism of the association. Neurons and astrocytes are strongly associated with the free water and the macroscopic organization.

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