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Abstract #1303

Investigating the influence of ECG-triggering and respiration strategy on renal perfusion quantification using arterial spin labelling

Irène Brumer1, Simon Jonscher1, Indre Gineitaite1, Rebeca Echeverria-Chasco2, Lothar R. Schad1, María Asunción Fernández-Seara2, and Frank G. Zöllner1
1Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 2Department of Radiology, ClĂ­nica Universidad de Navarra, Pamplona, Spain


In this study, we investigated the influence of ECG-triggering and respiration strategy choice on renal perfusion. To this end, pCASL data of healthy volunteers was acquired at 3T. Acquisitions and processing followed the PARENCHIMA consensus. Processing consisted of groupwise registration, manual whole kidney segmentation and automated cortex/medulla segmentation. All calculated perfusion values were close to the expected range for healthy individuals. Preliminary results from four subjects suggest the influence of cardiac cycle is negligible and the choice of respiration strategy has little effect on renal perfusion values calculated from pCASL data, however additional data is necessary for more complete evaluation.

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