Pulmonary transit time derived from routine perfusion cardiac magnetic resonance scans for non-invasive assessment of hemodynamics
Martin Segeroth1, David Winkel1, Shan Yang1, Alexander Sauter1, Jens Bremerich1, Michael Zellweger2, Christian Müller2, and Philip Haaf2
1Clinic for radiology and nuclear medicine, Universitätsspital Basel, Basel, Switzerland, 2Clinic for cardiology, Universitätsspital Basel, Basel, Switzerland
Pulmonary transit time (PTT) derived from routine cardiac magnetic resonance perfusion scans is a robust and easily obtainable noninvasive parameter of hemodynamics. PTT correlates with both LVEF, RVEF and NT-proBNP and could serve as a new global non-invasive parameter with a discriminative character for detecting cardiopulmonary dysfunction. We demonstrate that PTT has a high diagnostic accuracy in terms of exclusion and inclusion of heart failure as assessed by NT-proBNP, even in patients with preserved LVEF and RVEF.
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