Abstract #1310

BOLD MRI Perfusion in Peripheral Skeletal Muscle: Revealing the cuffing duration dependency

Stefanie Eriksson^1,2, Jonathan Arvidsson^1,2, Suhela Abubakar Mohammad¹, Edvin Johansson³, and Kerstin Lagerstrand^1,2

¹Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ²Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, ³Antaros Medical, Mölndal, Sweden

Synopsis

This study demonstrates the cuffing duration dependence of BOLD T2*-time curve parameters in peripheral skeletal muscle in the calf. This was made possible by the repeated measurements of healthy individuals using two different cuffing paradigms. The cuffing paradigms consisted of an ischemic period induced by cuffing of the thigh for 1.5 or 5 minutes, as well a 5 minute period of reactive hyperaemia. Systematic comparison of derived parameters was done from a descriptive representation of the T2* time curve.

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