Structural Brain Changes during Early Development in Non-human Primate, Common Marmoset: A Longitudinal MRI study
Akiko Uematsu1,2, Junichi Hata3, Makoto Fuskushima1, Noriyuki Kishi2, Ayako Muyarama2, Takuya Hayashi1, and Hideyuki Okano2,4
1BDR Laboratory for Brain Connectomics Imaging, RIKEN, Kobe, Japan, 2CBSLaboratory for Marmoset Neural Architecture, RIKEN, Wako, Japan, 3Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan, 4Department of Physiology, Keio University School of Medicine, Tokyo, Japan
Neuronal brain development at early life stage is critical for proper function at later life stages. Here, we delineate the maturational process of marmoset brain structure in both macro and micro level at very early life stage with longitudinal multi-modal MRI images. Integrating multi-modal MRI images provided more detailed and accurate information of changes in tissue property especially for frontal brain regions throughout development than a single-modal image analysis.
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