Abstract #1325

Structural Brain Changes during Early Development in Non-human Primate, Common Marmoset: A Longitudinal MRI study

Akiko Uematsu^1,2, Junichi Hata³, Makoto Fuskushima¹, Noriyuki Kishi², Ayako Muyarama², Takuya Hayashi¹, and Hideyuki Okano^2,4

¹BDR Laboratory for Brain Connectomics Imaging, RIKEN, Kobe, Japan, ²CBSLaboratory for Marmoset Neural Architecture, RIKEN, Wako, Japan, ³Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan, ⁴Department of Physiology, Keio University School of Medicine, Tokyo, Japan

Synopsis

Neuronal brain development at early life stage is critical for proper function at later life stages. Here, we delineate the maturational process of marmoset brain structure in both macro and micro level at very early life stage with longitudinal multi-modal MRI images. Integrating multi-modal MRI images provided more detailed and accurate information of changes in tissue property especially for frontal brain regions throughout development than a single-modal image analysis.

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