Meeting Banner
Abstract #1335

Quantitative analysis of dynamic-contrast enhanced MRI by dispersion analysis for improved prostate cancer diagnosis

Simona Turco1, Catarina Dinis Fernandes2, Razvan Miclea3, Ivo Schoots4, Peet Nooijen5, Hans van der Linden5, Jelle Barentsz6, Stijn Heijmink 7, Hessel Wijkstra2, and Massimo Mischi2
1Electrical Engineering, Eindhoven Univeristy of Technology, Eindhoven, Netherlands, 2Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 3Abdominal radiology, Maastricht University Medical Center, Maastricht, Netherlands, 4Abdominal radiology, Erasmus Medical Center, Rotterdam, Netherlands, 5Uropathology, Jeroen Bosch Ziekenhuis, 's-Hertogenbosch, Netherlands, 6Radiology, Radboud university medical center, Nijmegen, Netherlands, 7Radiology, Netherlands Cancer Institute, Amsterdam, Netherlands

Synopsis

Multiparametric MRI, including T2-weighted, diffusion-weighted, and dynamic contrast enhanced (DCE) imaging, is the recommended imaging modality for prostate cancer (PCa). Although the role of DCE-MRI has been greatly limited in recent years, only qualitative analysis of DCE is currently performed. Here we propose magnetic resonance dispersion imaging (MRDI) to obtain quantitative parametric maps from DCE-MRI. Comparing the performance of two radiologists, our results show that some clinically-significant PCa are only found by interpretation of either mpMRI alone or MRDI maps alone, suggesting that combined interpretation of MRDI and mpMRI may improve PCa diagnosis.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords