Respiratory motion is one of the major factors hindering accurate R2* mapping for hepatic iron quantification. In this work, motion-resolved 3D multi-echo UTE cones MRI with pseudo-random view ordering was implemented for motion-robust and free-breathing R2* mapping of hepatic iron. Compared to conventional gridding reconstruction, motion-resolved reconstruction reduced the overestimation of R2* induced by respiratory motion artifacts, enabling an accurate measurement of R2*. 3D multi-echo UTE cones MRI with motion-resolved reconstruction demonstrated the feasibility of accurate free-breathing R2* mapping for hepatic iron quantification.
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