Double-quantum filtered (DQF) deuterium spectra were obtained on a 3T scanner from lower leg and forearm muscles of volunteers whose deuterium abundance was increased by approximately 100 times through ingestion of deuterium oxide. Quadrupolar splitting frequencies of approximately 20 – 40 Hz were measured throughout the various muscle groups of the lower leg, with some regions showing little or no splitting. Although the DQF sequence considerably reduces the signal intensity, it has the advantage that it removes any isotropic signal component and therefore reveals an anisotropic component that might have been obscured.
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