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Abstract #1366

Metabolic information in APT-CEST  - A combined 1H and 31P MRS study

Jan-Ruediger Schuere1, Eike Steidl1, Elisabeth Neuhaus2, Manoj Shrestha3, Elke Hattingen1, and Ulrich Pilatus1
1Neuroradiology, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany, 2Goethe University Hospital Frankfurt, Frankfurt am Main, Germany, 3Brain Imaging Center, Goethe University, Frankfurt am Main, Germany

Synopsis

In this work, APT-CEST imaging in combination with 1H and 31P spectroscopy was performed to investigate 17 patients with different brain tumors. A synergistic analysis should help for a better understanding of the APT-CEST contrasts such as MTRasym with regard to tumor metabolism and further physiological relationships such as the pH-sensitivity.

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Keywords