Short-TE diffusion-MRI by combining strong gradients with ultrasonic readout
Aris van Ieperen1,2, Chantal Tax1,3, Dennis Klomp1, Bas Vermulst2, Jeroen Siero1,4, Joost van Straalen5, Martijn Heintges5, and Edwin Versteeg1
1Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 2Electromechanics & Power Electronics, Eindhoven University of Technology, Eindhoven, Netherlands, 3CUBRIC, School of Physics and Astronomy, Cardiff University, Cardiff, United Kingdom, 4Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 5Prodrive Technologies B.V., Son, Netherlands
For high-resolution diffusion-MRI, strong gradients combined with fast readout are desired. In this study, we propose a gradient system architecture for such strong gradients and fast readouts without nerve stimulation by implementing a filter topology that allows for both low and high frequency gradient waveforms. Two gradient inserts with different specifications are realized and two proposed modulation strategies are implemented in the amplifier firmware. Field measurements demonstrated the desired dual-mode capability of the system. With one gradient insert, a gradient amplitude of 300 mT/m and slew rates well above 10.000 T/m/s can be reached with only 500A&330V as amplifier output.
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