Abstract #1384

Multi-delay pseudo-continuous arterial spin labeling in head and neck healthy tissues

Nienke D. Sijtsema^1,2, Steven F. Petit¹, Dirk H.J. Poot², Gerda M. Verduijn¹, Esther A.H. Warnert², Mischa S. Hoogeman^1,3, and Juan A. Hernandez-Tamames²

¹Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, Netherlands, ²Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, ³Department of Medical Physics and Informatics, HollandPTC, Delft, Netherlands

Synopsis

Arterial spin labeling (ASL) has potential for response prediction of tumor and healthy tissue in the head and neck region after radiotherapy. Since little is known about blood flow (BF) values in this region, we measured BF and the repeatability of BF in several tissues simultaneously using multi-delay pseudo-continuous ASL. This enables investigation of the correlation between perfusion and severity of radiotherapy side-effects in a future study. Of the tissues we assessed, we found the parotids have the highest and the tonsils have the lowest perfusion.

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