In vivo, high-resolution Black Blood MRI at 7T
Eva Peschke1, Mariya Pravdivtseva1, Olav Jansen2, Naomi Larsen2, and Jan-Bernd Hövener1
1Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Schleswig - Holstein, Kiel University, Kiel, Germany, Kiel, Germany, 2Department of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein, Kiel University, Kiel, Germany, Kiel, Germany
Vessel wall imaging (VWI) is a unique method to depict the vessel walls in vivo but was not applied in small animal models at 7T yet. Here, we developed a setup to emulate T1 contrast and flow to optimize Black Blood MRI in vitro. Using the results, we implemented a RARE sequence that allows in vivo Black Blood MRI with a high resolution of 0.156 x 0.156 mm² and successful flow suppression. Next, the model will be extended for VWI to measure the enhancement of Gadolinium contrast agent.
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