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Abstract #1402

Feasibility of phase resolved functional lung imaging (PREFUL) with ultrashort echo time sequence (PUTE)

Lea Behrendt1,2, Marcel Gutberlet1,2, Andreas Voskrebenzev1,2, Filip Klimeš1,2, Arnd Obert1,2, Agilo Luitger Kern1,2, Frank Wacker1,2, and Jens Vogel-Claussen1,2
1Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany


Phase-resolved Functional Lung imaging (PREFUL) allows the contrast-free quantification of pulmonary ventilation and perfusion dynamics in free breathing. Typically, it is used in conjunction with cartesian spoiled gradient echo sequence (SPGRE) with asymmetric echo. Due to the short T2* times in lung tissue, acquiring signal with echo times as low as possible is essential. Therefore, a 2D ultrashort echo time sequence with a TE of 0.07ms was developed and tested in the PREFUL context in one healthy volunteer. A similar visual impression of derived ventilation maps was found with UTE and SPGRE. However, ventilation defects were more pronounced for UTE.

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