Meeting Banner
Abstract #1408

Simultaneous morphologic and quantitative imaging of the knee joint using pseudo-3D MIXTURE sequences: from deliberation to implementation

Teresa Nolte1, Shuo Zhang2, Nicola Pridöhl1, Malin Ciba1, Masami Yoneyama3, Christiane Kuhl1, and Sven Nebelung4
1Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany, 2Philips GmbH Market DACH, Hamburg, Germany, 3Philips Japan, Tokyo, Japan, 4Clinic for Diagnostic and Interventional Radiology, Uniklinik RWTH Aachen University, Aachen, Germany


This work aimed to propose a clinical sequence platform for simultaneous morphologic and quantitative imaging of joints and identified TSE-based MIXTURE (Multi-Interleaved X-prepared Turbo-Spin Echo with Intuitive Relaxometry) sequences in terms of PDFS-T2 and T1-TFS combinations for clinical implementation. Even though capable of isotropic resolution, MIXTURE sequences were acquired as pseudo-3D (thicker slices, higher in-plane resolution) to match standard-clinical 2D TSE sequences. After identification of clinical demands, MIXTURE sequences were systematically optimized, while maintaining clinically feasible acquisition times of 5:00 min (PDFS-T2 for T2-mapping) and 6:40 min (T1-TFS for T-mapping), and evaluated in a cadaveric human knee cartilage defect model.

This abstract and the presentation materials are available to members only; a login is required.

Join Here