Dark Blood, Susceptibility-Insensitive 3D Unbalanced Steady-State Free Precession: A Potential New Approach for Lung Cancer Screening
Robert R Edelman1,2, Bradley Allen2, Nondas Leloudas1, Jianing Pang3, and Ioannis Koktzoglou1,4
1Radiology, NorthShore University HealthSystem, Evanston, IL, United States, 2Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, 3Siemens Medical Solutions USA, Chicago, IL, United States, 4Radiology, Pritzker School of Medicine, University of Chicago, Chicago, IL, United States
We recently described the feasibility of using a prototype 3D unbalanced steady-state free precession (3D uSSFP) pulse sequence for dark blood imaging. We sought to determine whether this technique could be adapted for dark blood, susceptibility-insensitive imaging of the lungs. A breath-hold, ECG-gated version of 3D uSSFP was implemented for a pilot study of healthy volunteers and patients. Initial results suggest that 3D uSSFP allows efficient volumetric imaging of the lungs and can demonstrate even small lung nodules without artifacts. With further development, the technique could provide a radiation-free alternative to low-dose CT for lung cancer screening.
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