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Abstract #1479

Motion Compensation in Pulmonary Ultra-short Echo Time MRI: Preliminary Results in Neonatal Bronchopulmonary Dysplasia

Luis A. Torres1, Nara S. Higano2,3,4, Deep Gandhi4, Chamindu Gunatilaka2, Jason C. Woods2,3,4, and Sean B. Fain5
1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 2Division of Pulmonary Medicine, Cincinnati Children’s Medical Center, Cincinnati, OH, United States, 3Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States, 4Department of Radiology, Cincinnati Children’s Medical Center, Cincinnati, OH, United States, 5Department of Radiology, University of Iowa, Iowa City, IA, United States


Self-gating of free breathing pulmonary MR images remains challenging due to inconsistent tidal breathing and bulk motion especially in neonatal patients. We evaluate several conventional and advanced retrospective motion compensation techniques in neonatal subjects with lung disease of prematurity. Registration-based techniques show a significant improvement in signal to noise ratio and contrast to noise ratio relative to other motion compensation methods. There were no significant changes in sharpness across the cohort. We conclude that registration-based techniques could be used to improve image quality without loss of sharpness.

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