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Abstract #1493

Comparison of Two Methods for Measuring Knee Cartilage Thickness in Lower Extremities Using 7T Magnetic Resonance Imaging: A Cadaver Study

Dominik Vilimek1,2, Benedikt Hager3, Markus Schreiner4, Pavla Hanzlikova5,6, Radana Kahankova1, Veronika Janacova2, Didier Laurent7, Christoph Fuchssteiner8, Wolfgang Weninger8, Reinhard Windhager4, Pavol Szomolanyi2, Siegfried Trattnig2,3,9, and Vladimir Juras2
1Department of Cybernetics and Biomedical Engineering, VSBā€“Technical University of Ostrava, Ostrava, Czech Republic, 2High Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria, 3Institute for Clinical Molecular MRI in the Musculoskeletal System, Karl Landsteiner Society, Vienna, Austria, 4Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria, 5Department of Imaging Method, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic, 6Department of Imaging Method, University Hospital Ostrava, Ostrava, Czech Republic, 7Novartis Institutes for Biomedical Research, Translational Medicine, Basel, Switzerland, 8Center for Anatomy and Cell Biology, Division of Anatomy, Medical University of Vienna, Vienna, Austria, 9CD laboratory for Clinical Molecular MR imaging (MOLIMA), Vienna, Austria


Knee articular cartilage thickness may potentially serve as a marker for monitoring of the knee cartilage status. However, it is challenging to measure and quantify the articular cartilage thickness using in vivo MRI. In the present study, we evaluated 6 unpaired lower extremies of body donors using both a prototype segmentation software and a semi-automatic approach. Our results showed a low correlation (r = 0.45) between the two methods, indicating the challenge of determining cartilage thickness from MR images.

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