Abstract #1494
Correlation of Fractional Anisotropy and Histological Measures of Muscle Architecture in Vastus Lateralus in Legs with Injured ACL
Peter Andrew Hardy1, Christopher Fry2, Anders Andersen3, Katherine Thompson4, Thorsten Feiweier5, and Brian Noehren6
1Radiology, University of Kentucky, Lexington, KY, United States, 2Athletic Training and Clinical Nutrition, University of Kentucky, Lexington, KY, United States, 3MRISC, University of Kentucky, Lexington, KY, United States, 4Statistics, University of Kentucky, Lexington, KY, United States, 5Diagnostic Imaging, Siemens Healthcare, GmbH, Erlangen, Germany, 6Physical Therapy, University of Kentucky, Lexington, KY, United States
Synopsis
We measured diffusion tensor properties of the vastus lateralus muscle in 30 subjects who had a torn ACL. DTI was acquired with a stimulated echo acquisition with a diffusion time of 185 ms. From biopsies of the muscle taken simultaneously we developed histological measures of muscle fiber cross sectional area and minimum Feret diameter. Linear regression analysis demonstrated strong association of the fractional anisotropy and minimum Feret diameter.
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