In this study, we demonstrate the effectiveness of two de-noising methods on diffusion-weighted and dynamic lung imaging in healthy rats using 129Xe and 19F. While the results showed a insignificant difference for denoising method 1 (MP-PCA), de-noising method 2 (MP-PCA preceded by hard-thresholding over a nuclear norm in k-space) showed significant difference in the overall mean Lm and LmD values for ventilation and r (fractional ventilation estimate) for ventilation images.
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