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Abstract #1586

The effect of k-space sampling patterns on contrast agent uptake curves in dynamic contrast-enhanced MRI of the breast

Owen Alun White1, Evanthia Kousi1, Clarrissa Sanders2, and Maria Angelica Schmidt1
1Radioisotope & Imaging Physics, The Royal Marsden NHS Foundation Trust, London, United Kingdom, 2St George's University Hospital NHS Foundation Trust, London, United Kingdom

Synopsis

Here we propose a novel method to assess the effect of different k-space sampling patterns on contrast agent uptake curves (CAUCs), which does not require specialist equipment. These effects on CAUCs are often overlooked, and must be addressed in the context of the many different national and international recommendations, and the prominence given to abbreviated DCE protocols. We validated the method to assess different k-space sampling patterns and used it to simulate the effect on contrast-agent uptake curves. We show that conventional protocols acquiring each frame in approximately 60s have more robust CAUC classification than abbreviated protocols.

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